Proteins bind together via their interface. Some residues on the interface regions, play more important role than other residues in terms of contribution to binding. We call those residues “hotspots”. Considering their roles in binding, hotspots might be very promising drug targets for inhibition of unwanted protein interactions. My aim is to accurately predict hotspot residues by enhancing current detection algorithms.

M.Sc. Thesis: Turning the Spotlight on a Long-Overlooked Pathway: Molecular Dynamics Investigation of Ras Family Members with RalGDS.

Ph.D. Candidate Koç University, Computational Science and Engineering
M.Sc.  Koç University, Molecular Biology and Genetics
B.Sc. Istanbul Bilgi University, Genetics and Bio-engineering